‘The second is nanopores, which can be our oldest line of investigation and which has now led to DNA sequencers depending on nanopores. We pull personal DNA strands through a nanopore and may then go through off the nucleotide sequence. Very lately, we even managed to study out a single protein for the first time using This system. But this line of investigate is not simply about establishing equipment, but additionally about genuine Organic issues.

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Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I

Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.

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Microbiology has only existed for a century, because we started to research micro-organisms far more severely. I assumed nanobiology was an correct time period, because all molecular biological relevant interactions take place at the nanoscale: a protein is a couple of nanometres in dimension, DNA is 2 nm thick.’

All parameters have been the exact same for every panel in this video, except for the Preliminary placement in the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early as a consequence of translocation of the rod with the pore are marked by a grey track record.

2011, 1st in vitro measurements of transportation throughout one biomimetic nuclear pore advanced; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination

The rotors harness Electricity from a nanoscale water and ion move that is created by a static chemical or electrochemical prospective gradient within the nanopore, which are recognized by way of a salt gradient or used voltage, respectively. These synthetic nanoengines self-organize and run autonomously in physiological situations, suggesting methods to developing Vitality-transducing motors at nanoscale interfaces.

Bulk-area coupling identifies the mechanistic relationship between Min-protein patterns in vivo and in vitro

Screening pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments

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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook https://www.ceesdekker.net bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)